Evidence guide

How deHype grades claims

Learn how deHype evaluates health and science claims with a transparent grading system based on strength, relevance, and quality of evidence.

Evidence grades

Key idea

deHype grades combine evidence strength, human relevance and whether the public claim goes beyond the study.

deHype uses a clear grading system to help readers quickly understand whether a health or science claim is backed by strong evidence, early results, or only animal/cell studies. Our goal is to make it easier to see when a claim might be overstated or when results are not yet ready to guide decisions in humans.

Why does grading evidence matter?

Many published claims sound promising, but the sources and quality of evidence can vary a lot. A claim based on early studies in mice, for example, is very different from a claim supported by large, well-conducted studies in people. Grading helps you spot these differences at a glance.

What does deHype consider when grading a claim?

  • Type of study: Is the evidence from human studies (such as randomised controlled trials, observational studies), animal research, or lab (cell) experiments?
  • Study quality: Was the study well-designed? Did it include enough people? Was it randomised, controlled, or blinded?
  • Sample size: Larger studies generally provide more reliable results, especially when well-conducted.
  • Relevance to humans: Are the findings directly applicable to people, or have they only been seen in animals or cells?
  • Outcome type: Did the study look at a meaningful outcome for health, or just a surrogate marker (like a blood test or cell change)?
  • Replication: Have the findings been repeated by independent teams, or are they based on a single study?
  • Potential for overstatement: Does the claim accurately reflect what was found, or does it go beyond the evidence?

What do the grades mean?

  • Strong human evidence: Consistent results from high-quality human studies, with meaningful health outcomes. May be considered reliable for decision-making, but not absolute proof.
  • Early human evidence: Initial results in people, but based on smaller studies, short duration, or less certain outcomes. Promising, but needs more confirmation.
  • Animal/cell evidence: Findings only shown in animals or laboratory experiments, not yet tested or confirmed in people. These claims are usually the most speculative.
  • No evidence or anecdote: Claims based only on personal stories, testimonials, or arguments without supporting research. These should be treated with caution.

Limits of evidence grading

Even well-graded evidence can change as new research emerges. deHype grades are intended to give a quick overview, not definitive answers or personal advice. Always consult a qualified health professional for personal decisions.

Frequently Asked Questions

  • What is an evidence grade?
    It's a summary of how convincing the current research is for a specific claim, based on study quality and relevance.
  • Does a strong grade mean a claim is proven?
    No. Even strong evidence can change, and "proven" does not mean guaranteed for everyone. Grades reflect current knowledge.
  • Are animal studies useful?
    They provide early clues but do not guarantee results will be the same in humans.
  • Can I use deHype grades instead of medical advice?
    No. Grades are for information only and are not a substitute for talking to a healthcare professional.
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