Evidence quality

Lead-time bias

The appearance of longer survival because disease is detected earlier, not because death is delayed.

What it means

Definition

Lead-time bias. Lead-time bias is important in screening claims. Earlier diagnosis can increase measured survival time from diagnosis even when the actual time of death is unchanged.

What it can tell you

It can help clarify what sort of evidence or claim is being discussed.

What it cannot tell you

It cannot, by itself, prove that the headline is accurate or clinically important.

Headline trap

Why this matters in headlines

A screening test may appear to improve five-year survival without reducing mortality.