Evidence quality

Heterogeneity

Variation between studies, participants, interventions, or results.

What it means

Definition

Heterogeneity: Heterogeneity matters because pooled results may hide important differences. High heterogeneity makes simple summary claims less reliable.

What it can tell you

It can help clarify what sort of evidence or claim is being discussed.

What it cannot tell you

It cannot, by itself, prove that the headline is accurate or clinically important.

Headline trap

Why this matters in headlines

A meta-analysis of very different diets, populations, and outcomes may be hard to interpret.