Evidence quality

Confounder

A third factor that can distort the apparent relationship between an exposure and an outcome.

What it means

Definition

Confounder. A confounder is linked to both the exposure and the outcome, making an association look causal when it may not be. Observational studies try to adjust for confounders, but residual confounding often remains possible.

What it can tell you

It can help clarify what sort of evidence or claim is being discussed.

What it cannot tell you

It cannot, by itself, prove that the headline is accurate or clinically important.

Headline trap

Why this matters in headlines

If coffee drinkers exercise more, exercise could partly explain lower disease rates attributed to coffee.