Study design

Control group

The comparison group used to judge what would happen without the tested exposure or intervention.

What it means

Definition

Control group. A control group gives context to the intervention or exposed group. Without it, changes over time may reflect natural recovery, background trends or measurement variation rather than the intervention.

What it can tell you

It can show how close the evidence is to a real human health outcome.

What it cannot tell you

It cannot prove that a treatment works in people unless human outcome data are available.

Headline trap

Why this matters in headlines

A before-and-after claim is weaker if there is no comparable control group.